Chemical transformation of eremofortin C into PR toxin.
نویسندگان
چکیده
The natural products of both eremofortin C (EC) and PR toxin are secondary metabolites of Penicillium roqueforti. Because the chemical structures of EC and PR toxin are closely related to each other and differ only by a hydroxyl functional group in EC and an aldehyde functional group in PR toxin at the C-12 position, the chemical transformation of EC into PR toxin was investigated. Oxidation with a chromic anhydride-pyridine complex was found to be the most satisfactory method.
منابع مشابه
Isolation and Some Properties of the Enzyme That Transforms Eremofortin C to PR Toxin.
PR toxin and eremofortin C are secondary metabolites of Penicillium roqueforti. The chemical structures of these two compounds are closely related to each other and differ only by an aldehyde and an alcohol group at the C-12 position. In an effort to better understand the biosynthesis of PR toxin, we discovered the enzyme of P. roqueforti that is responsible for the transformation of eremoforti...
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عنوان ژورنال:
- Applied and environmental microbiology
دوره 50 3 شماره
صفحات -
تاریخ انتشار 1985